By the time most health economists get pulled in, the recipe is already set. In this episode of MAP — the Market Access Podcast, Dr. Stefan Walzer sits down with two industry veterans — Dr. Björn Schwander, Founder of AHEAD GmbH and a specialist in early health economic modeling, and Julie Frappier, senior health economist and Founder of TOWWERS — to make the case for moving early health economics upstream.
The conversation reframes value as more than a financial number: the combination of clinical relevance, economic relevance, and affordability, aligned early across the “five Ps” — patients, prescribers, policymakers, payers, and producers. Björn and Julie explain why early models should be deliberately simple, built to test scenarios and surface the strongest value signals rather than chase false precision, and why embracing uncertainty is a feature, not a flaw. They also tackle the implementation risk too often ignored — illustrated by a CAR-T case in Quebec where it took a full year to treat the first patient after approval — and why an early “no-go” can be just as valuable as a green light.
LinkedIn: Dr. Björn Schwander https://www.linkedin.com/in/bjoern-schwander-phd-672040b/
Julie Frappier https://www.linkedin.com/in/julie-frappier-b5642a3/
